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| Galtung N.. Diehl-Wiesenecker E., Lehmann D., Markmann N., Bergström W.H., Wacker J.,
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| Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department
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| Eur J Emerg Med. 2022 Apr 21. doi: 10.1097/MEJ.0000000000000931
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| Buturovic L., Zheng H., Tang B., Lai K., Kuan W.S., Gillett M., Santram R., Shojaei M., Almansa R., Nieto J.A., Munoz S., Herrero C.,
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Abstract |
| A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections
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| Scientific Reports 12, Article number: 889
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| Bauer W., Kappert K., Galtung N., Lehmann D., Wacker J., Cheng H,K., Liesenfeld O.,
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Abstract |
| A Novel 29-Messenger RNA Host-Response Assay From Whole Blood Accurately Identifies Bacterial and
Viral Infections in Patients Presenting to the Emergency Department With Suspected Infections: A
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| Crit Care Med. 2021 Oct; 49(10): 1664-1673
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| Mayhew M.B., Tran E., Choi K., Midic U., Luethy R., Damaraju N., Buturovic L. (2021)
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| Optimization of Genomic Classifiers for Clinical Deployment: Evaluation of Bayesian Optimization to Select Predictive Models of Acute Infection
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| Biocomputing 2021, pp. 208-219
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| Buturovic L., Zheng H., Tang B., Lai K., Kuan W.S., Gillett M., Santram R., Shojaei M., Almansa R., Nieto J.A., Munoz S., Herrero C.,
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| A 6-mRNA host response whole-blood classifier trained using patients with non-COVID-19 viral infections accurately predicts severity of COVID-19
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| Mayhew M.B., Tran E., Choi K., Midic U., Luethy R., Damaraju N., Buturovic L. (2020)
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| Optimization of Genomic Classifiers for Clinical Deployment: Evaluation of Bayesian Optimization to Select Predictive Models of Acute Infection and In-Hospital Mortality
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| arXiv:2003.12310
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| Mayhew M.B, Buturovic L., Luethy R., Midic U., Moore A.R., Roque J.A., Shaller B.D., Asuni T.,
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| A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections
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| Nature Communications volume 11, Article number: 1177
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| Zhao H., Atkinson J., Gulesserian S., Zeng Z., Nater J., Ou J.W.,
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| Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates.
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| Cancer Research 78(8), 2115-2126.
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| Kani K., Faca V.M., Hughes L.D., Zhang W., Fang Q., Shahbaba B.,
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| Quantitative Proteomic profiling identifies protein correlates to EGFR kinase inhibition.
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| Mol Cancer Ther. 2012 Mar 21. [Epub ahead of print]
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| Luethy R., Kessner D.E., Katz J.E., MacLean B., Grothe R.,
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| Precursor-Ion Mass Re-estimation Improves Peptide Identification on Hybrid Instruments.
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| J Proteome Res. Sep;7(9), 4031-9.
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| Luethy R. and Hoover C. (2004)
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| Hardware and software systems for accelerating common
bioinformatics sequence analysis algorithms.
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| BioSilico 2(1), pp. 12-17
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| Zhu J. and Lüthy R. (2002)
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| Three-dimensional structure prediction using simplified structure
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| Davis M.T., Beierle J., Bures E.T., McGinley M.D., Mort J.,
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| Automated LC-LC-MS-MS platform using binary ion-exchange and gradient
reversed-phase chromatography for improved proteomic analyses.
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| J Chromatogr B Biomed Sci Appl 752(2), 281-91.
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| Spahr C.S., Davis M.T., McGinley M.D., Robinson J.H., Bures E.J.,
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| Towards defining the urinary proteome using liquid
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| Davis M.T., Spahr C.S., McGinley M.D., Robinson J.H., Bures E.J.,
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Luethy R., Patterson S.D. (2001)
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| Towards defining the urinary proteome using liquid
chromatography-tandem mass spectrometry II.
Limitations of complex mixture analyses.
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| PROTEOMICS 1 (1), 108-117.
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| Zhu J., Lüthy R., and Lawrence C.E. (1999)
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| Database search based on Bayesian alignment.
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| Proceedings, Seventh International Conference on Intelligent Systems
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| Hu M.C., Qiu W.R., Wang Y.P., Hill D., Ring B.D., Scully S., Bolon
B., DeRose M., Lüthy R., Simonet W.S., Arakawa T. and Danilenko D.M.
(1998)
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Abstract |
| FGF-18, a novel member of the fibroblast growth factor family, stimulates
hepatic and intestinal proliferation.
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| Molecular and Cellular Biology 18 (10), 6063-6074.
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| Alexandrov, N.N. and Lüthy, R. (1998)
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Abstract |
| Alignment algorithm for homology modeling and threading.
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| Protein Science 7, 254-258.
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| Courchesne P.L., Jones M.D., Robinson, J.H., Spahr, C.S., McCracken, S.,
Bentley, D.L., Lüthy, R., and Patterson, S.D. (1998)
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Abstract |
| Optimization of capillary chromatography ion-trap mass spectrometry
for identification of gel-separated proteins.
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| Electrophoresis, 19 (6), 956-967.
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| Maryanski, J.L., Casanova, J.-L., Falk, K., Gournier, H., Jaulin, C., Kourilsky,
P., Lemonnier, F.A., Lüthy, R., Rammensee, H.-G., Rötzschke,
O., Servis, C., and Lopez, J.A. (1997)
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Abstract |
| The diversity of antigen-specific TCR repertoires reflects the relative
complexity of epitopes recognized.
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| Human Immunology, 54, 117-128.
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| Eisenberg, D., Lüthy, R., and Bowie, J.U. (1997)
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| VERIFY3D: Assessment of protein models with three-dimensional profiles.
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| Meth. Enzymol., 277, 396-404.
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|
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| Simonet, W.S., Lacey, D.L., Dunstan, C.R., Kelley, M., Chang, M.-S.,
Lüthy, R., Nguyen, H.Q., Wooden, S., Bennett, L., Boone, T.,
Shimamoto, G., DeRose, M., Elliott, R., Colombero, A., Tan, H.-L.,
Trail. G., Sullivan, J., Davy, E., Bucay, N., Renshaw-Gegg, L.,
Hughes, T.M., Hill., D., Pattison, W., Campbell, P., Sander, S., Van,
G., Tarpley, J., Derby, P., Lee, R., Amgen EST Program, and Boyle, W.J. (1997)
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Abstract |
| Osteoprotegerin: A novel secreted protein involved in the regulation
of bone density.
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| Cell, 89(2), 309-319.
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| Shutter, J.R., Graham, M., Kinsey, A.C., Scully, S., Lüthy, R.,
and Stark, K.L. (1997)
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Abstract |
| Hypothalamic expression of ART, a novel gene related to agouti, is
up-regulated in obese and diabetic mutant mice.
|
| Genes & Development, 11(5), 593-602.
|
|
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| Courchesne P.L., Lüthy, R., and Patterson, S.D. (1997)
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Abstract |
| Comparison of in-gel and on-membrane digestion methods at low to sub
pmol level for subsequent peptide and fragment-ion mass analysis using
matrix-assisted laser-desorption/ionization mass spectrometry.
|
| Electrophoresis, 18, 369-381.
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| Lüthy, R., Xenarios, I., and Bucher, P. (1994)
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Abstract |
| Improving the sensitivity of the sequence profile method.
|
| Protein Science, 3(1), 139-146.
|
|
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| Maryanski, J.L., Lüthy, R., Romero, P., Healy, F., Drouet, C.,
Casanova, J.-L., Jaulin, C., Kourilsky, P., and Corradin, G. (1993)
|
Abstract |
| The interaction of antigenic peptides with the H-2Kd MHC class I molecule.
|
| Seminars in Immunology, 5(2), 95-104.
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| Lüthy, R., Bowie, J.U. and Eisenberg, D. (1992)
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Abstract |
| Assessment of protein models with three-dimensional profiles.
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| Nature 356, 83-85.
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| Eisenberg, D., Bowie, J.U., Lüthy, R. and Choe S. (1992)
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Abstract |
| Three-dimensional profiles for analysing protein sequence-structure
relationships.
|
| Faraday Discuss. 93, 25-34.
|
|
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| Held, W., Shakov, A.N., Waanders, G., Scarpellino, L., Lüthy, R.,
Kraehenbul, J.-P., MacDonald, H.R., and Acha-Orbea, H. (1992)
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Abstract |
| An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7)
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| J. Exp. Med., 175, 1623-33.
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| Lovejoy, B., Le, T.C., Lüthy, R., Cascio, D., O'Neil, K.T.,
DeGrado, W.F. and Eisenberg, D. (1992)
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|
| X-ray grade crystals of a designed alpha-helical coiled coil peptide.
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| Protein Science, 1 (7), 956-957
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| Frutiger, S., Hughes, G.J., Paquet, N., Lüthy, R. and Jaton, J.C. (1992)
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| Disulfide bond assignment in human J chain and its covalent pairing
with immunoglobulin M.
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| Biochemistry, 31 (50), 12643-12647.
|
|
|
| Bowie, J.U., Lüthy, R. and Eisenberg, D. (1991)
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Abstract |
| A method to identify protein sequences that fold into a known
three-dimensional structure.
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| Science 253, 164-170.
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| Lüthy, R., McLachlan, A.D. and Eisenberg, D. (1991)
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Abstract |
| Secondary structure-based profiles: use of structure-conserving scoring
tables in searching protein sequence databases for structural similarities.
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| PROTEINS: Structure, Function, and Genetics 10, 229-239.
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| Lüthy, R. and Eisenberg, D. (1991)
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| Chapter 2: Protein.
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| in: Sequence Analysis Primer, ed. M. Gribskov and J. Devereux, 1991
Stockton Press, New York, 61-87.
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| Gribskov, M., Lüthy, R., and Eisenberg, D. (1990)
|
|
| Profile Analysis
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| Meth. Enzymol. 183, 146-159
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| Lüthy, R., and Azzi, A. (1989)
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Abstract |
| Reconstitution of the mitochondrial tricarboxylate carrier and a novel
enzymatic assay for its activity.
|
| Anal. Biochemistry 177, 323-326.
|
|
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| Lüthy, R., and Azzi, A. (1987)
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Abstract |
| Fluorescent and photoactive probes for the study of protein kinase C.
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| Eur. J. Biochem. 162 (2), 387-91.
|
|
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| Mahoney, C.W., Lüthy, R., and Azzi, A. (1987)
|
|
| Trans--membrane signaling via protein kinase C and its inhibition by
staurosporine.
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| in: Dynamics of membrane proteins and cellular energetics,
ed. N. Latruffe,Y. Gaudemer, P. Vignais, and A. Azzi, 1988, Springer Verlag, pp. 13-23
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| Mahoney, C.W., Lüthy, R., and Azzi, A. (1986)
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| Membrane signal transduction via protein kinase C.
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| in: Membrane proteins, ed. by A. Azzi, L. Masotti, A. Vecli, 1986 Springer
Verlag, pp. 56-66.
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| Deranleau, D.A., Lüthy, R., and Lüscher, E.F. (1986)
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Abstract |
| Stochastic responses of human blood platelets to stimulation of shape
change and secretion.
|
| Proc. Natl. Acad. Sci. 83 (7), 2076-B80.
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|
